模块化内嵌分支支架形态特征对支架内血流动力学的影响
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国家自然科学基金项目(12002231,11802195),北京市自然科学基金项目(7212095)


Influences of Morphological Characteristics of Modular Inner Branched Stent Graft on Hemodynamic Performance of Stent
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    摘要:

    目的 基于模块化内嵌分支支架(modular inner branched stent graft,MIBSG)的参数化模型,研究该支架形态特征对术后支架内血流动力学特征的影响。方法 求解血流和MIBSG相互作用的流固耦合模型,分析分支支架的分支角度和管径对支架内血流动力学特征影响。结果 随着分支支架与主动脉弓支架之间的角度增大,分支内的血流量降低,受到的应力和产生的位移增大。分支支架的管径减小,血流量灌注会显著下降,应力和位移却先增大后减小。结论 MIBSG形态变化不仅影响分支支架的血流灌注率,还会影响支架所受应力和产生的位移。临床上使用该类型支架治疗主动脉弓部病变前,需要在手术预案中根据实际情况充分考虑支架的走向和扭转。

    Abstract:

    Objective To study the effect of morphological characteristics of modular inner branched stent graft (MIBSG) on hemodynamic performance of postoperative aortic arch based on parameterized MIBSG model. Methods The fluid-structure interaction model of blood-MIBSG coupling performance was solved, and the effects of stent branch angles, stent diameters on hemodynamic characteristics were analyzed. Results With the increase of angles between branch stent and aortic arch stent, blood flow within the branch decreased, but the stress and displacement increased. With the decrease of stent diameters, blood flow perfusion decreased significantly, but the stress and displacement increased first, and then decreased. Conclusions The morphological changes of MIBSG not only have an impact on blood perfusion rate of branch stent, but also affect the stress exerted on stent and the corresponding displacement. Before application in clinic treatment of aortic arch diseases, the movement and torsion of MIBSG should been taken into full account in operation plan according to the actual situation.

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马晓丹,李芬,朱雅亭,刘帅媛,陈凌峰,田海平.模块化内嵌分支支架形态特征对支架内血流动力学的影响[J].医用生物力学,2022,37(1):124-130

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  • 收稿日期:2021-02-05
  • 最后修改日期:2021-04-08
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  • 在线发布日期: 2022-02-25
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