目的 运用有限元方法分析手性蜂窝夹层结构椎体植入物的应力分布规律，为指导椎体压缩性骨折的临床治疗提供理论依据。方法 建立三韧带手性蜂窝夹层结构椎体植入物的三维有限元模型，结合正交实验法和面内外尺寸效应分析进行结构参数优化设计，并分析五种不同工况下的应力大小及分布。 结果 应力峰值最小的结构参数组合为：胞元壁厚0.28mm，面板厚度0.8mm，胞元高度0.2mm，韧带长度0.6mm，应力峰值出现在蜂窝层边缘靠近上下面板的部分，应变最大处位于上面板边缘未受蜂窝芯子支撑的部分。 结论 优化设计后的手性蜂窝夹层结构满足人体生理载荷，植入椎体后应力峰值比正六边形蜂窝夹层结构更小，应力分布更均匀，适合作为椎体植入物基本结构。
Objective To provide a theoretical basis for the clinical treatment of vertebral compression fractures, finite element method was used to analyze the stress distribution of vertebral implants with chiral honeycomb sandwich structure. Methods A trichiral honeycomb sandwich structure was constructed as the 3-D finite element model of the vertebral implant.The structural parameters was optimized by combining orthogonal experiment with the size effect in-plane and out-of plane,and the stress of the five different loadings was analyzed. Results The combination of structural parameters with the minimum stress peak value was as follows: cell wall thickness 0.28mm, panel thickness 0.8mm, cell height 0.2mm, ligament length 0.6mm.The stress peak occurs at the edge of the honeycomb core near the upper and lower panels, and the maximum strain is located at the edge of the upper panel which is not supported by the honeycomb core. Conclusions After optimized design, the chiral honeycomb sandwich structure can meet the physiological load of human body, and the stress peak value after implantation is smaller than that of the regular hexagonal honeycomb sandwich structure, and the stress distribution is more uniform, which is suitable for the basic structure of vertebral implant.