髋膝关节置换患者骨质疏松管理专家共识(2025年版)
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上海市东方英才拔尖计划(BJWS2024020),上海市教委人工智能跃升计划项目重点项目(JWAIZD-7)


Expert Consensus on Osteoporosis Management in Patients Undergoing Hip or Knee Arthroplasty (2025 Edition)
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    摘要:

    随着人口老龄化的加快,骨关节系统疾病尤其是髋膝关节疾病日益成为全球性健康问题。人工关节置换手术作为髋膝关节疾病进展至终末期的标准治疗方案,因其疗效明确,临床应用范围不断扩大,手术量持续攀升。与此同时,接受髋膝关节置换患者的骨质疏松症发生率居高不下,近2/3存在低骨量或者骨质疏松,而在手术时接受规范抗骨质疏松治疗者不足1/3。骨质疏松是导致关节置换术后假体周围骨丢失、假体无菌性松动、假体周围骨折及翻修风险增加的重要危险因素,显著影响患者预后及假体长期生存率。尽管骨质疏松症的临床治疗方案已较为成熟,但在髋膝关节置换患者这一特殊人群中,围手术期骨健康评估、干预时机及治疗策略尚未形成统一标准。为规范髋膝关节置换患者骨质疏松的诊断与围手术期及术后骨质量优化管理,由中华医学会骨科学分会关节外科学组组织国内相关领域专家,共同制定《髋膝关节置换患者骨质疏松管理专家共识(2025版)》。本共识围绕髋膝关节置换术前骨健康评估、围手术期及术后骨质疏松干预时机与方案、手术方式及假体选择、术中及术后骨质疏松相关并发症的预防、术后康复及骨密度监测等方面提出13条推荐意见,旨在构建髋膝关节置换骨质疏松患者的骨质疏松管理体系,降低假体相关并发症及翻修率,改善患者长期预后,为临床实践提供循证依据。

    Abstract:

    With the accelerating aging of the global population, diseases of the osteoarticular system, especially hip and knee disorders, have increasingly become a worldwide health concern. As the standard treatment for end-stage hip and knee diseases, total joint arthroplasty (TJA) has witnessed expanding clinical application and a steady surge in surgical volume due to its proven efficacy. However, the incidence of osteoporosis remains high among patients undergoing hip and knee arthroplasty—nearly two-thirds of these patients have low bone mass or osteoporosis, while the treatment rate for osteoporosis at the time of arthroplasty is less than one-third. Osteoporosis is a key factor contributing to periprosthetic bone loss, aseptic loosening of the prosthesis, periprosthetic fractures, and increased revision risk after joint replacement, which severely impacts patient prognosis and long-term prosthetic survival. Despite the availability of mature clinical treatment protocols for osteoporosis, unified standards have not yet been established for perioperative bone health assessment, timing of intervention, and treatment strategies in patients undergoing hip and knee arthroplasty. To standardize the diagnosis of osteoporosis and optimize perioperative and postoperative bone health management in this patient population, Joint Surgery Branch of the Chinese Orthopedic Association organized domestic experts in related fields to jointly formulate the Expert Consensus on Osteoporosis Management in Patients Undergoing Hip and Knee Arthroplasty (2025 Edition). This consensus puts forward 13 recommendations covering pre-operative bone health assessment, timing and protocols of perioperative and postoperative osteoporosis intervention, surgical planning and prosthesis selection, prevention of osteoporosis-related complications during and after surgery, as well as postoperative rehabilitation and bone mineral density monitoring. The aim is to improve the bone optimization system for hip and knee arthroplasty in osteoporotic patients, reduce prosthesis-related complications and revision rates, improve long-term prognosis, and provide evidence-based guidance for clinical practice.

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胡越皓,翟赞京,柴伟,杨佩,陈云苏,何川,张国强,张晓岗,朱晨,毛新展,谢杰,李凭跃,吴浩波,胡宁,冯尔宥,严孟宁,毛远青,常永云,谢凯,陈逍堃,张经纬,顾洁梅,汪海娅,盛辉,蔡斌,朱振安,曹力,周勇刚,王坤正,李慧武.髋膝关节置换患者骨质疏松管理专家共识(2025年版)[J].医用生物力学,2025,40(6):1372-1388

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  • 收稿日期:2025-11-30
  • 最后修改日期:2025-12-08
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  • 在线发布日期: 2025-12-25
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