心脏瓣膜计算机建模仿真研究进展
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复旦大学生物医学工程与技术创新学院

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Recent Progress on Computational Modeling and Simulation of Heart Valves
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College of Biomedical Engineering, Fudan University

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    摘要:

    随着经导管心脏瓣膜置换术和修复术的快速发展,心脏瓣膜的建模仿真在心脏瓣膜产品研发、风险评估、手术规划等方面获得了越来越广泛地应用,并且发挥着越来越重要的作用。而随着人工智能在建模仿真领域的快速发展,心脏瓣膜建模仿真也呈现出一些新的发展方向和趋势,特别是快速建模和仿真使得基于建模仿真的术前规划成为可能。本文对近十多年来心脏瓣膜建模仿真的相关进展进行总结和分析,包括主动脉瓣、肺动脉瓣、二尖瓣、三尖瓣等心脏的四个瓣膜及瓣膜疾病各种治疗器械,涵盖几何建模方法、数学物理建模方法、数值仿真算法、临床应用等领域。同时对心脏瓣膜建模仿真中的工程问题和难点以及其在器械研发和临床手术规划中的应用进行系统的总结和展望。

    Abstract:

    With the rapid development of transcatheter heart valve replacement and repair, heart valve modeling and simulation have been increasingly applied in heart valve product development, risk assessment, and surgical planning, playing an increasingly important role. At the same time, with the rapid advancement of artificial intelligence in the field of modeling and simulation, heart valve modeling and simulation also show some new development directions and trends, especially rapid modeling and simulation, which make preoperative planning based on modeling and simulation possible. This paper summarizes and analyzes the relevant progress of heart valve modeling and simulation over the past decade, covering the four heart valves— aortic, pulmonary, mitral, and tricuspid—as well as various devices for valve diseases, including geometric modeling methods, mathematical and physical modeling methods, numerical simulation algorithms, and clinical applications. At the same time, it systematically summarizes and forecasts the engineering problems and challenges in heart valve modeling and simulation, as well as its applications in device development and clinical surgical planning.

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  • 收稿日期:2026-01-31
  • 最后修改日期:2026-03-03
  • 录用日期:2026-03-03
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