Objective By comparing the fatigue strength of type A and type B locking compression plates (LCP) in the distal femoral plate, a theoretical evaluation method is provided for the selection of the plate when testing its bending strength and fatigue performance. Methods Through the bending strength performance test and fatigue performance test of different types of bone plates, combined with the finite element analysis of the total deformation, von-Mises stress and fatigue service life of the bone plates by ANSYS Workbench, the bone plates are selected. Results The fatigue strength of type A plate is 30.7% higher than that of type B plate, the stress of type A plate is lower than that of type B plate, and the minimum fatigue life of type A plate is 17% higher than that of type B plate. Conclusion The fatigue performance of type A plate is better than that of type B plate, so the possibility of failure of type A plate is lower than that of type B plate; The research significance of this article is mainly to assist in the selection of different bone plates when testing the performance of the two newly developed bone plates.