Mechanical Virtual Human of China is a key research project supported by National Natural Science Foundation.A human musculoskeletal system will be built, and this system will be able to export transformed individualizedmusculoskeletal geometric model for specific human parameters. Motion capture system will be employed to measurehuman motion and results will be transformed into musculoskeletal model motion. Through kinematics, kinetics and forceanalysis, joint and muscle forces can be determined for whole process of a specific motion. The musculoskeletal systemis also a finite element model, and FE analysis can be performed for global or local skeletal components. A large scalesoftware system will be developed to support all these calculations and analyses, and this software system will findwide applications in such areas as medical engineering, medical instrument design, physical and art education, ergonomicsand traffic accident analysis.