THE IN VIVO MECHANICAL PROPERTIES OF BIOABSORBABLE HIGH STRENGTH POLY-L-LACTIDE MATERIAL
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    Abstract:

    Objective to investigate the mechanical properties of the bioabsorbable solid-state compression reinforced high strength poly-L-lactide (SC-PLLA) material in vivo Methods SC-PLLA rods (3.2mm×30mm) were made by a special heating compression - the solid-state compression process. The morphological properties and the mechanical strengths (bending and shear strength) of the rods were investigated succesivly after the rods were implanted in rabbits subcutanously and in bone. Results Tuenty-four weeks after implantation the bending and shear strength of SC PLLA rods remained above 180 Mpa and 75Mpa respectively. They were higher than the strength of human cortical bone. The shear strength decreased faster than the bending strength. Under the scanning electron microscope numerous ordered fibers could be seen longitudinal to the axis of the rod inside the SC-PLLA material. After implantation the fibers could be degraded with time and the material become porotic. Conclusion Solid-compression process could obtain high initial and retention strength PLLA which could fit for the general bone internal fixation. SC-PLLA is a promising bioabsorbable osteosynthetic material.

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. THE IN VIVO MECHANICAL PROPERTIES OF BIOABSORBABLE HIGH STRENGTH POLY-L-LACTIDE MATERIAL[J]. Journal of medical biomechanics,2001,16(3):135-139

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